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ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) will increase the stage or effect of ergotamine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Acute ergot toxicity characterised by vasospasm and tissue ischemia has actually been connected to coadministration of ritonavirErgotism manifested by rigorous arterial vasoco